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List of experimental and computational labs focusing on IDPs. In the last ten years, a great number of laboratories have investigated protein disorders using both experimental (e.g. SAXS-NMR, single-molecule fluorescence) and computational (analysis of protein structure) techniques. * Keith Dunker coined the term IDP, recognised IDPs as distinct class of proteins with important biological functions, established many prediction algorithms to characterise IDPs in thousands of proteomes. * Peter Tompa contributed early studies of oversized IDPs and disordered plant chaperones. * Vladimir Uversky is a pioneer in theoretical and experimental biophysics of IDPs.〔https://hsccf.hsc.usf.edu/facultyDirectory/researchDirectory/search_profile.cfm?person_id=2838234〕 * Madan Babu is a pioneer in cellular regulation of IDPs and studied how IDP expression and degradation are controlled. * Jim Bardwell is a pioneer in the discovery of intrinsically disordered molecular chaperones. * Ursula Jakob is a pioneer in conditional disorder and its role for molecular chaperoning. * Philipp Selenko is a pioneer in in-cell characterisation of IDPs. * Michael Woodside pioneered optical tweezers studies on aggregation. * Sir Alan Fersht pioneered structural studies on the most frequently cancer-mutated IDP, p53. * Stefan Rudiger is a pioneer in Hsp90-associated IDP recognition mechanisms. * Tobias Madl pioneered SAXS-NMR protein complex determination methodology development. * Yongli Zhang is a pioneer in IDP unfolding. * Peter Wright pioneered the mechanistic analysis of coupled folding and binding of IDPs. * Jane Dyson is a pioneer in NMR studies on various biologically important IDPs. * Rohit Pappu pioneered modelling of electrostatic malleability of IDP ensembles. and developed powerful modeling tools to predict ensembles of highly charged IDPs based on their charge distributions. * Inke Nathke pioneered research on APC, one of the largest IDPs. * Madelon Maurice is a pioneer in cellular mechanisms of IDP scaffolds in Wnt signalling. * Richard Kriwacki pioneered structural studies on binding-induced folding of IDPs. * Benjamin Schuler pioneered single-molecule fluorescence studies on IDPs. * Ashok Deniz pioneered single-molecule fluorescence studies on IDPs. * David Klenerman pioneered single-molecule fluorescence studies on IDPs. * Vincent Hilser extended the theory of allostery and demonstrated that IDPs have an ensemble allosteric advantage. * Yosef Shaul pioneered large-scale experimental investigations of IDPs in cells using 20S Proteasome assays. * David Eliezer pioneered NMR and ESR studies on IDPs such as alpha-synuclein and tau. ==See also== * List of disorder prediction software 抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「List of experimental and computational labs focusing on IDPs」の詳細全文を読む スポンサード リンク
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